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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RIPK4 All Species: 23.03
Human Site: S381 Identified Species: 50.67
UniProt: P57078 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P57078 NP_065690 832 91611 S381 F D N D Y S L S E L L S Q L D
Chimpanzee Pan troglodytes XP_001134659 786 86619 S335 F D N D Y S L S E L L S Q L D
Rhesus Macaque Macaca mulatta XP_001107026 786 86655 S335 F D N D Y S L S E L L S Q L D
Dog Lupus familis XP_544897 826 90932 S375 F D S D Y S L S E L L S Q L D
Cat Felis silvestris
Mouse Mus musculus Q9ERK0 786 86594 S335 F D N D C S L S E L L S Q L D
Rat Rattus norvegicus P0C8E4 606 67182 P198 G S A A W M A P E V F E G S N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511321 791 87316 S335 F D A D Y S L S E L L S Q L D
Chicken Gallus gallus XP_416738 789 87316 G350 G I S Q T M E G P E D L S R S
Frog Xenopus laevis NP_001080415 720 79835 A312 Q G K V G K E A E P Q N M T S
Zebra Danio Brachydanio rerio Q502K3 1071 114412 S488 E V N E R D R S G C T P L H Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001180763 1378 147477 D456 E V N E V E K D R W I A L H F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.5 92.6 83.2 N.A. 84.9 23 N.A. 77.5 72.1 61.6 22 N.A. N.A. N.A. N.A. 21.4
Protein Similarity: 100 93.9 93.5 88.3 N.A. 89.3 38.9 N.A. 85.6 83.7 72.9 35.8 N.A. N.A. N.A. N.A. 34.9
P-Site Identity: 100 100 100 93.3 N.A. 93.3 6.6 N.A. 93.3 0 6.6 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 26.6 N.A. 93.3 6.6 20 20 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 19 10 0 0 10 10 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 0 55 0 55 0 10 0 10 0 0 10 0 0 0 55 % D
% Glu: 19 0 0 19 0 10 19 0 73 10 0 10 0 0 0 % E
% Phe: 55 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % F
% Gly: 19 10 0 0 10 0 0 10 10 0 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 19 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 10 0 0 10 10 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 55 0 0 55 55 10 19 55 0 % L
% Met: 0 0 0 0 0 19 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 55 0 0 0 0 0 0 0 0 10 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 10 10 10 0 10 0 0 0 % P
% Gln: 10 0 0 10 0 0 0 0 0 0 10 0 55 0 0 % Q
% Arg: 0 0 0 0 10 0 10 0 10 0 0 0 0 10 0 % R
% Ser: 0 10 19 0 0 55 0 64 0 0 0 55 10 10 19 % S
% Thr: 0 0 0 0 10 0 0 0 0 0 10 0 0 10 0 % T
% Val: 0 19 0 10 10 0 0 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 46 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _